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Tim cook speaks about running Apple and the legacy of Steve Jobs
Tim Cook's interview at the D10 Conference returned several times to Steve Jobs, his legacy at Apple, what he meant to Cook, and how Apple may or may not be changing since Jobs passed away.
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14 awesome tag team finishing maneuvers
In the aftermath of their monumental win against United States Champion Santino Marella & Zack Ryder on the May 11 edition of SmackDown, the tag team of Darren Young & Titus O?Neil asked one simple question of the WWE Universe: ?Do you all know the difference between [us] and the rest of the tag teams here in WWE??
Their ?million dollar? charisma notwithstanding, the promising duo could also distinguish themselves with the one thing they already have in common with some of the greatest duos in WWE history: a distinct tag team finishing maneuver.
While the backbreaker hold-diving elbow drop combination that Young & O?Neil execute may bolster their place in the win column, the timing and chemistry required to pull off that kind of impressive move also gives the up-and-coming partnership a distinct advantage over many of WWE?s top ranked tag teams.
Moreover, Young & O?Neil's impressive endgame brings them into elite company, as they join a proud tradition of WWE pairings who have used the power of teamwork to deliver a devastating knockout blow to their opponents. To see how their climactic finale stacks up, WWE.com takes a look at 14 signature finishers that other tag teams have relied upon to rough up a rival in the ring.
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Brazil Real Estate More Affordable Thanks To Currency Rates
As the Brazilian Real weakens against the US Dollar and the British Sterling, real estate in the country is now more affordable. In the summer of last year, an investor could get 1.56 Reals for each USD, and now they can get around 2. That means a house that cost 200,000 Reals last year would have cost $128,205 USD - now it would only be $100,000. For more on this, continue reading the following article from Property Wire.
The strength of Sterling against the Brazilian Real means that for British buyers property in Brazil is even more affordable, it is claimed.
Sterling is trading at a two and a half year high against the Brazilian Real and this means that if you bought a five star two bedroom beachfront apartment south of Natal on 01 June 2011 it would have cost ?111,617 but now the cost is ?90,564, according to Samantha Gore, sales manager of Brazil specialist estate agents uv10.
?From early June 2011 until now the Brazilian Real has been fading against the Pound, to the tune of 28%. Likewise, the US Dollar is at a two and a half year high and the Euro a two year high against Brazil?s currency,? she said.
She pointed out that a very attractive Brazil property buying scenario has come about by the retreat of the Real. The Eurozone collapse has sent shockwaves over to Brazil as investors fear that demand for this Latin American nation?s exports could drop sharply as an at least partial Eurozone breakup becomes increasingly likely.
Brazilian Finance Minister Guido Mantega is pleased that the Real is losing value and therefore becoming more competitive. ?The weak real is beneficial for the Brazilian economy because it makes Brazilian products more competitive, which means that Brazilian industry can better compete with imported products that become more expensive, and can export more,? he said recently.
Gore believes that optimism in Brazil extends further. ?The middle class continues to grow, fuelling demand for property and keeping prices on an upward trajectory, at least for a few more years. Benchmark interest rates have just been lowered to 9%, which is great news for local buyers eyeing a mortgage and developers seeking finance for new projects,? she explained.
?In 2014, the FIFA World Cup comes to Brazil and then Rio de Janeiro takes on Olympic hosting duties in 2016. Once these events have passed, there will still be huge oil exploration to keep Brazil in the spotlight and in the money. Meanwhile tourist arrivals continue to rise, further fuelling the country?s economy which managed 2.75% GDP growth in 2011,? she added.
Figures also show that last year Brazil welcomed a record number of visitors. Ministry of Tourism data shows there were 5.4 million visitors, 5.3% up on 2010?s figures. Best Western International has responded by opening its 17th hotel in Brazil, but the first from its Best Western Premier brand, the five star Best Western Premier Majestic Ponta Negra Beach, one the most famous beaches in Brazil.
?
Best Western International aims to have 20 hotels in Brazil by 2017 and Marriott is also adding 12 hotels to its five existing properties in Brazil as it predicts a hotel room shortage throughout the sporting events calendar.
Gore pointed out that two bedroom properties at Golden Fields, Natal, start from around ?48,800.
This article was republished with permission from Property Wire.
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Wednesday, May 30, 2012
96% Moonrise Kingdom
All Critics (92) | Top Critics (24) | Fresh (88) | Rotten (4) | DVD (1)
Its moments of transporting beauty and visual brilliance overcame my growing aversion to Wes Anderson's brand of ultra-stylized archness.
We may look back on Anderson's works as we do on the boxes of Joseph Cornell -- formal troves of frippery, studded with nostalgic private jokes, that lodge inexplicably in the heart. In Moonrise Kingdom, that lodging is already under way.
It makes you nostalgic for the pangs of young love.
What makes it an Anderson movie are the things he adds which mark all his films - the pop-cultural obsessions and excruciatingly detailed set decorations, overarching thematic concerns and little stylistic tics.
I liked this one because of its young performers, the evocative island setting (filmed in Rhode Island), Alexandre Desplat's lovely score and Robert Yeoman's slightly grainy cinematography.
The director's best film since 1998's Rushmore, it has none of the self-conscious smugness of The Life Aquatic or the empty eccentricity of The Royal Tenenbaums.
A gossamer fable of adolescent romance, played out with the cheekily whimsical, visually delicious style for which Anderson is famous.
Wes Anderson's most sartorially significant film yet.
At once funny and melancholic, whimsical and poignantly true.
One is at times reminded of AE Housman.
Moonrise Kingdom is a delight... stuffed full of the quirky details and gags that are Anderson's trademarks, but it also possesses an emotional undertow that will tug at those viewers in tune with its singular sensibility.
Capturing our inner children
If the deadpan sensibility of the film ultimately leaves it feeling a tad lightweight, that isn't to say that Moonrise Kingdom isn't a funny, witty and well-crafted film.
Typically quirky Wes Anderson dramedy has lots of heart.
A bittersweet and evocative period piece that's both a visual and narrative delight.
No one has an eye or sensibility like Anderson's, but this is a chilly disappointment. The unaffecting kids are meant to be the emotional center, yet the adults steal the film.
I really wanted to like this film. I respect Wes Anderson and his distinctive voice as a writer-director ('Rushmore' is one of my favorite films of the 1990s), but this latest endeavor is so precious and self-aware that it nearly smothers itself.
Those who find the director's work flawed by preciousness, however, may grow impatient well before the movie reaches the 90-minute mark.
Anderson has imagined the '60s on the East Coast as if from an Eddie Bauer catalog and Boys' Life, with the sensibility of The New Yorker.
Like many holiday locations, you wouldn't want to live there, but a mini-break from the norm can be a real tonic.
A sweet, charming and altogether delightful bit of whimsy from writer/director Wes Anderson.
I normally end up liking Wes Anderson's films, but I love this one.
The delightful Moonrise Kingdom marks a career high for offbeat auteur Wes Anderson.
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Travel + Leisure: America's Worst-Dressed People (PHOTOS)
When it comes to dress sense, what's worse: layer upon bulky layer of long underwear and puffy coats? Flashy, barely-there outfits? Or downright sloppiness?
Travel + Leisure readers rated major destinations in categories including style for the annual America's Favorite Cities survey -- and the results confirm that city dwellers fall short of fashionable in myriad ways. But it's Anchorage that earned the dubious honor of No. 1 worst-dressed city in America.
That's no surprise to Dr. Miriam Jones, a paleoclimatologist who has traveled in and out of Anchorage "too many times to count" during a two-year research stint.
"It's not uncommon to see oversized parkas with fur-lined hoods and bunny boots," she says. "And people aren't alarmed when a person wearing a ski mask enters a room." In Alaska, she adds, men sport beards and flannel in the most unironic way possible: to keep frostbite at bay and their appendages attached.
Dressing well certainly has an element of personal taste, and this survey is based on visitors' perceptions, not scientific fact. So, did T+L readers deem your city to be one of America's worst dressed? Read on to find out, and feel free to defend local fashions in the comments.
-- Jessica Adamiak
More From Travel + Leisure:
America's Best Cities for Hipsters
America's Best Burger Cities
Strangest Travel Phobias
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Follow Travel + Leisure on Twitter: www.twitter.com/TravlandLeisure
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Household Product And Furniture - Home Improvement Made Easy
Doing home improvement is a wonderful way to get a lovely home that is suited to your own needs; it can also help you to save money. There can be a lot to remember when it comes to doing home improvements right, though, so here are some tips to help keep you working smart, as well as working hard.
If you have clear glass in your windows, your home could lose 20% of its heating and cooling. Installing an additional glaze to larger windows is a great way to conserve energy, thus lowering your energy costs.
Before starting a job, decide what you will do beforehand. Developing a plan is a very important part of finishing your project on time and under budget. Adding new work and new goals to a project that?s already underway can strain your budget and your schedule much more seriously than you might expect. Contractors will also be happier if you already have a good idea of what it is you want.
If you want to reduce your costs and beef up your home?s security profile, add motion sensing lights to your property. These lights consume less energy by switching on only in the presence of movement. Intruders will also think twice about approaching your home, since their presence is highlighted when the lights flick on.
Improve your home?s windows! Give your windows a makeover! Try out double glazed windows. They aren?t your cheapest choice, but they are cost-effective in the long run. Improving your windows can also increase your overall security. If you are not able to get new windows, paint the window sills or frames, or simply change your drapes.
Make sure that your caulking is in good shape. Inspect the caulking in your tub and sink areas regularly. If the caulk has cracked or developed small holes, moisture can seep into your walls creating mold and mildew. If water starts seeping through the holes and cracks in your caulking, it will find its way into the flooring, and eventually the floor will start rotting. To properly caulk, remove all old caulk, thoroughly clean the area and allow it to dry. You will achieve the best seal from the new caulk when you have a clean surface.
These tips can aid you in mastering your home improvement project. They will help give your home a personalized touch and improve its resale value. It can only get better the more effort you put in, after all ? at least if you follow smart advice like this to make sure you do home improvements properly!
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Google Nexus tablet appears in benchmarks, appears to run on quad-core Tegra 3
ASUS's seven-inch MeMo tablet has just ducked under the FCC's gates, but some benchmark results for a purported Google and ASUS team-up could tally with the same device. According to the listing, the Google Asus Nexus 7 will arrive with NVIDIA's quad-core Tegra 3 CPU, clocked at 1.3 GHz, while that (presumably) 7-inch screen packs a 768 x 1280 resolution. The hardware specs end there, but thanks to some investigation by Android Police and Rightware, it appears that this mystery tablet is running Android 4.1 -- possibly the version number for Android's next iteration, Jelly Bean. There are several more hints adding credence to these benchmark results, including the fish-based "grouper" codename, which follows the Stingray moniker that was handed to the Motorola Xoom ahead of its reveal. We're just itching to know whether it'll still manage a sub-$300 price-tag.
Google Nexus tablet appears in benchmarks, appears to run on quad-core Tegra 3 originally appeared on Engadget on Wed, 30 May 2012 04:59:00 EDT. Please see our terms for use of feeds.
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What Remodeling Your Rest room Can do For the Home ...
When we typically think of residence enhancement projects, including a lavatory remodeling venture, we often think of what that challenge can do for us, personally. When it is possible to very easily benefit, numerous unique approaches, from getting your bathroom remodeled. Did you also know that your home can benefit at the same time The truth is that your house, itself, can benefit from a bathroom remodeling venture, often in far more ways than one particular.
Just before you are able to begin to understand the advantages that your home could check here out reap from a lavatory remodeling job, it truly is a very good notion to focus on what a lavatory remodeling undertaking is. Based on who you talk to, you might get various definitions of a home improvement undertaking. While you?ll find some who state that a lavatory remodeling task are only able to be regarded as remodeling if all of it?s altered, you will discover other individuals who claim that simply changing your bathtub is adequate to constitute a rest room remodeling challenge. Whatever your bathroom remodeling schemes are, no matter whether they only entail replacing your bathtub or changing about your whole bathroom, your home can nevertheless benefit from the modifications produced.
Maybe, the biggest lavatory remodeling benefit that your property will see might be an enhance in value. Nearly all houses that go through a lavatory remodeling job wind up viewing an improve find here in worth. This can be simply because practically all bathroom remodeling projects result in some thing superior. Although a modest rest room remodeling task may well result in an boost in value, the larger projects are frequently types that generate the biggest differences in value. In spite of the reality that many homes do see an boost in worth, following a bathroom remodeling project continues to be finished, it can be significant to notice that not all houses to. If your rest room remodeling venture was badly completed or never ever obtained finished, you could actually locate that your home?s overall value decreases. That is certainly why it can be important that all tasks not merely get finished, but that they get completed ideal.
Apart from an improve in worth, a bathroom remodeling venture may well assist to strengthen the look of one?s home. As formerly pointed out, most lavatory remodeling projects are done to boost a lavatory, quite simply, make it better than it was there ahead of. Regardless of whether your home just didn?t appear appealing or if your bathroom necessary repairs to make it safe once more, your rest room could drastically benefit from a new facelift. In fact, you may uncover that your lavatory not simply appears superior, but so does the remainder of your home.
Although it is nice to understand what a rest room remodeling venture can perform for your residence, you could also be wondering what it could do for you. As mentioned above, property owners generally end up benefiting, in a quantity of different techniques, from a rest room remodeling job. Several of those benefits are, in a way, associated the appearance of one?s house or rest room. Given that rest room remodeling tasks just about usually result in some thing greater, you, as a home-owner, may possibly really feel proud of your new lavatory. In actual fact, you might feel as in the event you got a whole new bathroom. Due to the fact there is a great opportunity that you will be happy with the changes, you may uncover yourself additional prepared to invite your buddies or family to arrive into your home; thus resulting in an entire other set of benefits.
As you could readily see, you?ll find an limitless quantity of advantages to getting your rest room remodeled; positive aspects that might not just use to you, but to your residence also. If would prefer to experience quite a few with the over pointed out advantages, you?re suggested to acquire began nowadays. The sooner you start off your lavatory remodeling challenge, the earlier you can be pleased with all the finish result.
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Tuesday, May 29, 2012
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Just how to be able to Achieve Effective Customer Retention
The two state that whenever a business typically is able to achieve many fast customers, the two are generally positive to keep within surgery for lots of lengthy years. This might be the ways customer retention functions. It is very the particular responsibility of an business that would retain the entire loyalty of their customers or alternatively new customers to get repeat sales and / or business from many of these people. This particular is the reason why various businesses would definitely do usual promotions, deals and additionally benefits. It happens to be as well precisely why almost all companies would certainly train their staff members to be courteous plus respectful in order to their customers or perhaps visitors. These tend to be all approaches to achieve customer retention. These days, indeed there usually are at this point competitive methods to retain customers on to a business. Customer loyalty can really result to more income as well as stability for a business. At this site are generally several techniques to achieve efficient fitness business customer retention despite almost all the competition which companies are generally facing nowadays.
Generally there is one thing that you want to recognize to be able to achieve the actual utmost personal trainer customer retention for the business; not to mention which typically is customer reassurance. Whether or not buyers do all competitive techniques to retain the entire loyalty of the shoppers, they might never do if the two happen to be definitely not happy with your own goods as well as services. So, begin off by giving top quality service to all your own customers whether or not historic and / or modern. Be sure that your needs acquire their trust simply just at the actual begin of your transaction alongside them. Equally, make them feel comfortable alongside your business. Do not do anything that can irritate them. And additionally keep them pleased always. This might be the particular reason precisely why the majority of businesses would certainly actually train their staff members to be courteous and even how that would offer quality customer service. Bear in mind that your particular business ought to constantly be pals alongside a buyers. If your clients include felt solid dealing alongside you, afterward the two surely comes in return for more purchases.
The next thing which you need to look after is your goods. Make sure you may have the entire treatments that people usually get in return that would over plus over once again. Regardless of what you're providing, be sure that it is inside useful quality not to mention which persons will certainly be pleased whenever the two employ it. Shoppers are generally particularly hunting for things they will certainly furthermore learn how to trust for a wide range of many years that would come. Never offer products which usually really dismay new customers considering you'll never go far from many of these products. Offer something that adults will acquire in return in order to continuously from buyers.
Doing business is actually not simply just about fulfilling your individual goals; it is actually also regarding offering exactly what will give advantages to your own valued clients and keeping them fast that would your individual business. Without your customers, your business will certainly never succeed. The particular value which us give in order to the clients will certainly furthermore return that would anyone through the actual loyalty of your customers. This might be the ways a business will be lucrative, profitable and also stable. Check this video for more about personal training client retention.
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SpaceX flyby of space station an historic first
The SpaceX Dragon capsule successfully made its first burn to approach the space station at 3:58 a.m Thursday. It was the final test before the SpaceX capsule docks at the ISS.
This computer generated image shows the SpaceX Dragon spacecraft with solar panels deployed. The world's first private supply ship flew tantalizingly close to the International Space Station on Thursday, May 24, 2012 in a critical test in advance of the actual docking scheduled for Friday, May 25, 2012.
AP Photo/SpaceX
EnlargeA private spaceship on its first trip to the International Space Station made a flyby of the orbiting laboratory early Thursday (May 24), zipping just below the outpost in an unprecedented space first.
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The unmanned vehicle, called?Dragon, is built by Space Exploration Technologies Corp. (SpaceX), and is the first commercial spacecraft ever launched toward the space station. During the rendezvous, the spacecraft approached within 1.6 miles (2.5 km) of the outpost. Dragon launched to orbit??from Cape Canaveral, Fla.,?early Tuesday (May 22) atop a SpaceX Falcon 9 rocket and is due to arrive at the station on Friday (May 25).
Today was a?final testing day for the capsule?before it can be cleared to attempt its first docking. The capsule performed a near flyby of the space station just as designed, without any mishap.
IN PICTURES: SpaceX Falcon 9 rocket
"Today is a really great day," NASA flight director Holly Ridings said during a briefing after the flyby. "It's been very, very successful up to this point."
Crewmembers inside the orbiting lab have been monitoring the vehicle's activities.
"We all look forward to it," space station Expedition 31 flight engineer Andre Kuipers of the European Space Agency said this morning. "We will dedicate today to Dragon." [SpaceX's Historic Dragon Flight to Space Station]
The capsule successfully made its first burn to approach the space station at 3:58 a.m. EDT (0758 GMT), and followed with another engine firing at 4:43 a.m. EDT (0843 GMT) that took Dragon to a position 1.6 miles (2.5 km) below and 25 miles (40 km) behind the?International Space Station, officially beginning its flyby. At around 7:25 a.m. EDT (1125 GMT), Dragon made its closest approach, passing through the imaginary line called the R-bar connecting the station and Earth.
From this spot, cameras on the outpost searched for sightings of the approaching capsule.
"Dragon may or may not be visible," NASA commentator Josh Byerly said. "Dragon should be a small dot on the horizon."
Shortly before 7 a.m. EDT (1100 GMT), station astronauts sent instructions to Dragon to turn on a strobe light as a test to make sure the craft can respond to commands sent by the astronauts. Though the light was invisible to the crew, the spacecraft's systems indicated that the command was received and responded to.
"It's too far out and brightly illuminated to see the strobe light," Kuipers said.
The space station is a $100 billion orbiting research lab built by a coalition of five international space agencies, including NASA, the Russian Federal Space Agency, the European Space Agency, the Japanese Aerospace Exploration Agency, and the Canadian Space Agency.
During Thursday's flyby, Dragon tested its navigation and communications instruments, including a system called Relative GPS that uses the distance between the station and the capsule to determine Dragon's position in space. The vehicle will also tried out its "COTS Ultra-high frequency Communication Unit" to send signals to the space station.
As Dragon approached the station, the spacecraft was visible as a small bright dot in the distance.
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AP Photos: Americans honor troops for Memorial Day
Boy Scouts carry a large American flag through the Memphis National Cemetery in Tennessee, where scouts also placed flags on 42,000 graves. In Little Rock, Ark., a 4-year-old girl fills her arms with flags to place on graves.
Across the U.S. this weekend, Americans are honoring the fallen, veterans and military personnel in ceremonies and private remembrances.
Here's a gallery of AP photos from Memorial Day weekend.
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Enyo's End Is Not Nigh
Most of HP's webOS team, including Matt McNulty, head of the project, is moving to Google according to a report by The Verge citing several unnamed sources. The departing team is said to be almost wholly responsible for Enyo's code. Enyo replaced Mojo as webOS's software development kit in 2011.
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Costless Bankruptcy Tips and advice ? Finding a Bankruptcy Attorney
Are you getting a difficult time dealing with your complete debt? Do you want to find an attorney to help you to via the complicated strategy of your bankruptcy, or are you currently unsure whether or not bankruptcy is the best best option? How when you start choosing the right lawyer? How will you know irrespective of whether that lawyer is respected, reliable, while offering a good value?
1. First, there is absolutely no conisder that you ought to have to cover an appointment fee. There are numerous highly qualified lawyers that come with free consultations and can permit you the opportunity ask questions and understand the options without having to agree to hiring them. Obtain an attorney that offers free consultations, and reap the benefits of this time to question questions and see what that exact attorney suggests the the person could do on your behalf.
2. Find out if your attorney knowledge in consumer bankruptcy. Ask the lawyer if she or he has filed either chapter seven and chapter 13 cases and if she / he includes found these cases to a discharge to your client. A discharge could be the energy that the bankruptcy court has to destroy many, if not all, of your debts to provide you a fresh start and clean record financially.
3. Ask the attorney what their own fees are, and whether it?ll cost you by the hour or possibly a flat, foreseen fee. It is not necessarily always bad somebody who is attorney charges constant, but there has to be a very good explanation for why they do. There?s lots of attorneys which will charge a flat, predictable fee that could allow you to insurance policy for your expenses. It?s not necessarily always cognizant of look for the absolute bottom-of-the-barrel bankruptcy lawyer to manage your case. Things get it wrong in bankruptcy cases, and slack attorney work by rubbish, ?cheap? lawyers can find themselves costing far more sometime soon as additional legal tasks are essential to either keep case or fix conditions have developed because of wrong or insufficient awareness of detail.
4. See if your lawyer is accessible. Will it be challenging for yourself to speak with a real, live attorney once you call the office? Will you finally end up on the telephone with helper, clerk, paralegal, and after that law student when you contact? Does your probable lawyer return your phone calls and reply to emails within round the clock and answer the questions you have?
Finally, a vey important factor might be the main one least more likely in your radar. What precisely did your gut tell you? In case you felt like you were conversing with or met by having an honest and reputable lawyer, it is likely you were. If you ever felt just like you were addressing a person that was interested only with your money and may not be available to enable you to supply the eye you require, you may be right about that too.
For those who are in Chicago and searching for chicago bankruptcy attorney, I suggest you to visit chicago bankruptcy web-site.
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Too much vitamin D can be as unhealthy as too little
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 29-May-2012[ | E-mail |
Share ] Contact: Darshana Durup, Ph.D.
dd@farma.ku.dk
01-145-617-05192
University of Copenhagen
Scientists know that Vitamin D deficiency is not healthy. However, new research from the University of Copenhagen now indicates that too high a level of the essential vitamin is not good either. The study is based on blood samples from 247,574 Copenhageners. The results have just been published in the reputed scientific Journal of Clinical Endocrinology and Metabolism.
Vitamin D is instrumental in helping calcium reach our bones, thus lessening the risk from falls and the risk of broken hips. Research suggests that vitamin D is also beneficial in combating cardiac disease, depression and certain types of cancers. The results from a study conducted by the Faculty of Health and Medical Sciences now support the benefits of vitamin D in terms of mortality risk. However, the research results also show higher mortality in people with too high levels of vitamin D in their bloodstream:
"We have had access to blood tests from a quarter of a million Copenhageners. We found higher mortality in people with a low level of vitamin D in their blood, but to our surprise, we also found it in people with a high level of vitamin D. We can draw a graph showing that perhaps it is harmful with too little and too much vitamin D," explains Darshana Durup, PhD student.
If the blood contains less than 10 nanomol (nmol) of vitamin per liter of serum, mortality is 2.31 times higher. However, if the blood contains more than 140 nmol of vitamin per liter of serum, mortality is higher by a factor of 1.42. Both values are compared to 50 nmol of vitamin per liter of serum, where the scientists see the lowest mortality rate.
More studies are needed
Darshana Durup emphasises that while scientists do not know the cause of the higher mortality, she believes that the new results can be used to question the wisdom of those people who claim that you can never get too much vitamin D:
"It is important to conduct further studies in order to understand the relationship. A lot of research has been conducted on the risk of vitamin D deficiency. However, there is no scientific evidence for a 'more is better' argument for vitamin D, and our study does not support the argument either. We hope that our study will inspire others to study the cause of higher mortality with a high level of vitamin D," says Darshana Durup. She adds:
"We have moved into a controversial area that stirs up strong feelings just like debates on global warming and research on nutrition. But our results are based on a quarter of a million blood tests and provide an interesting starting point for further research."
The largest study of its kind
The study is the largest of its kind and it was only possible to conduct it because of Denmark's civil registration system, which is unique in the Nordic countries. The 247,574 blood samples come from the Copenhagen General Practitioners Laboratory:
"Our data material covers a wide age range. The people who participated had approached their own general practitioners for a variety of reasons and had had the vitamin D level in their bloodstream measured in that context. This means that while the study can show a possible association between mortality and a high level of vitamin D, we cannot as yet explain the higher risk," explains Darshana Durup.
Therefore in future research project scientists would like to compare the results with information from disease registers such as the cancer register. Financial support is currently being sought for such projects.
###
Contact:
PhD student
Darshana Durup
University of Copenhagen
The Faculty of Health and Medical Sciences
Mobile: +45 61 70 51 92
Mail: dd@farma.ku.dk
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 29-May-2012[ | E-mail |
Share ] Contact: Darshana Durup, Ph.D.
dd@farma.ku.dk
01-145-617-05192
University of Copenhagen
Scientists know that Vitamin D deficiency is not healthy. However, new research from the University of Copenhagen now indicates that too high a level of the essential vitamin is not good either. The study is based on blood samples from 247,574 Copenhageners. The results have just been published in the reputed scientific Journal of Clinical Endocrinology and Metabolism.
Vitamin D is instrumental in helping calcium reach our bones, thus lessening the risk from falls and the risk of broken hips. Research suggests that vitamin D is also beneficial in combating cardiac disease, depression and certain types of cancers. The results from a study conducted by the Faculty of Health and Medical Sciences now support the benefits of vitamin D in terms of mortality risk. However, the research results also show higher mortality in people with too high levels of vitamin D in their bloodstream:
"We have had access to blood tests from a quarter of a million Copenhageners. We found higher mortality in people with a low level of vitamin D in their blood, but to our surprise, we also found it in people with a high level of vitamin D. We can draw a graph showing that perhaps it is harmful with too little and too much vitamin D," explains Darshana Durup, PhD student.
If the blood contains less than 10 nanomol (nmol) of vitamin per liter of serum, mortality is 2.31 times higher. However, if the blood contains more than 140 nmol of vitamin per liter of serum, mortality is higher by a factor of 1.42. Both values are compared to 50 nmol of vitamin per liter of serum, where the scientists see the lowest mortality rate.
More studies are needed
Darshana Durup emphasises that while scientists do not know the cause of the higher mortality, she believes that the new results can be used to question the wisdom of those people who claim that you can never get too much vitamin D:
"It is important to conduct further studies in order to understand the relationship. A lot of research has been conducted on the risk of vitamin D deficiency. However, there is no scientific evidence for a 'more is better' argument for vitamin D, and our study does not support the argument either. We hope that our study will inspire others to study the cause of higher mortality with a high level of vitamin D," says Darshana Durup. She adds:
"We have moved into a controversial area that stirs up strong feelings just like debates on global warming and research on nutrition. But our results are based on a quarter of a million blood tests and provide an interesting starting point for further research."
The largest study of its kind
The study is the largest of its kind and it was only possible to conduct it because of Denmark's civil registration system, which is unique in the Nordic countries. The 247,574 blood samples come from the Copenhagen General Practitioners Laboratory:
"Our data material covers a wide age range. The people who participated had approached their own general practitioners for a variety of reasons and had had the vitamin D level in their bloodstream measured in that context. This means that while the study can show a possible association between mortality and a high level of vitamin D, we cannot as yet explain the higher risk," explains Darshana Durup.
Therefore in future research project scientists would like to compare the results with information from disease registers such as the cancer register. Financial support is currently being sought for such projects.
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Contact:
PhD student
Darshana Durup
University of Copenhagen
The Faculty of Health and Medical Sciences
Mobile: +45 61 70 51 92
Mail: dd@farma.ku.dk
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Monday, May 28, 2012
Family values
Public release date: 28-May-2012[ | E-mail |
Share ] Contact: Catherine Crawley
ccrawley@nimbios.org
865-974-9350
National Institute for Mathematical and Biological Synthesis (NIMBioS)
Faithful females who choose good providers key to evolutionary shift to modern family, study finds
In early human evolution, when faithful females began to choose good providers as mates, pair-bonding replaced promiscuity, laying the foundation for the emergence of the institution of the modern family, a new study finds.
The study helps answer long-standing questions in evolutionary biology about how the modern family, characterized by intense, social attachments with exclusive mates, emerged following earlier times of promiscuity. In addition to the establishment of stable, long-lasting relationships, the transition to pair-bonding was also characterized by a reduction in male-to-male competition in favor of providing for females and providing close parental involvement.
The study demonstrates mathematically that the most commonly proposed theories for the transition to human pair-bonding are not biologically feasible. However, the study advances a new model showing that the transition to pair-bonding can occur when female choice and faithfulness, among other factors, are included. The result is an increased emphasis on provisioning females over male competition for mating.
The effect is most pronounced in low-ranked males who have a low chance of winning a mate in competition with a high-ranked male. Thus, the low-ranked male attempts to buy mating by providing for the female, which in turn is then reinforced by females who show preference for the low-ranked, "provisioning" male, according to author Sergey Gavrilets, associate director for scientific activities at the National Institute for Mathematical and Biological Synthesis and a professor at the University of Tennessee-Knoxville.
"Once females begin to show preference for being provisioned, the low-ranked males' investment in female provisioning over male-to-male competition pays-off," Gavrilets explained.
Gavrilets says that the study's results describe a "sexual revolution" initiated by low-ranking males who began providing in order to get matings. "Once the process was underway, it led to a kind of self-domestication, resulting in a group-living species of provisioning males and faithful females," he said.
The study reveals that female choice played a crucial role in human evolution and that future studies should include between-individual variation to help explain social dilemmas and behaviors, according to Gavrilets.
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Citation: Gavrilets S. 2012. Human origins and the transition from promiscuity to pair-bonding. Proceedings of the National Academy of Sciences. [Online].
The National Institute for Mathematical and Biological Synthesis (NIMBioS) brings together researchers from around the world to collaborate across disciplinary boundaries to investigate solutions to basic and applied problems in the life sciences. NIMBioS is sponsored by the National Science Foundation, the U.S. Department of Homeland Security, and the U.S. Department of Agriculture with additional support from The University of Tennessee, Knoxville.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 28-May-2012[ | E-mail |
Share ] Contact: Catherine Crawley
ccrawley@nimbios.org
865-974-9350
National Institute for Mathematical and Biological Synthesis (NIMBioS)
Faithful females who choose good providers key to evolutionary shift to modern family, study finds
In early human evolution, when faithful females began to choose good providers as mates, pair-bonding replaced promiscuity, laying the foundation for the emergence of the institution of the modern family, a new study finds.
The study helps answer long-standing questions in evolutionary biology about how the modern family, characterized by intense, social attachments with exclusive mates, emerged following earlier times of promiscuity. In addition to the establishment of stable, long-lasting relationships, the transition to pair-bonding was also characterized by a reduction in male-to-male competition in favor of providing for females and providing close parental involvement.
The study demonstrates mathematically that the most commonly proposed theories for the transition to human pair-bonding are not biologically feasible. However, the study advances a new model showing that the transition to pair-bonding can occur when female choice and faithfulness, among other factors, are included. The result is an increased emphasis on provisioning females over male competition for mating.
The effect is most pronounced in low-ranked males who have a low chance of winning a mate in competition with a high-ranked male. Thus, the low-ranked male attempts to buy mating by providing for the female, which in turn is then reinforced by females who show preference for the low-ranked, "provisioning" male, according to author Sergey Gavrilets, associate director for scientific activities at the National Institute for Mathematical and Biological Synthesis and a professor at the University of Tennessee-Knoxville.
"Once females begin to show preference for being provisioned, the low-ranked males' investment in female provisioning over male-to-male competition pays-off," Gavrilets explained.
Gavrilets says that the study's results describe a "sexual revolution" initiated by low-ranking males who began providing in order to get matings. "Once the process was underway, it led to a kind of self-domestication, resulting in a group-living species of provisioning males and faithful females," he said.
The study reveals that female choice played a crucial role in human evolution and that future studies should include between-individual variation to help explain social dilemmas and behaviors, according to Gavrilets.
###
Citation: Gavrilets S. 2012. Human origins and the transition from promiscuity to pair-bonding. Proceedings of the National Academy of Sciences. [Online].
The National Institute for Mathematical and Biological Synthesis (NIMBioS) brings together researchers from around the world to collaborate across disciplinary boundaries to investigate solutions to basic and applied problems in the life sciences. NIMBioS is sponsored by the National Science Foundation, the U.S. Department of Homeland Security, and the U.S. Department of Agriculture with additional support from The University of Tennessee, Knoxville.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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