Saturday, December 17, 2011

Griffin says his Twitter warning was a warning for everyone

Griffin says his Twitter warning was a warning for everyoneMiguel Torres is gone. Let's hope it's a short stay in exile.

If he returns to the UFC, it won't erase what's gone down on Twitter with the fighters and it certainly doesn't mean that a future blow up isn't right around the corner. Managing verbal gaffes on Twitter will be an ongoing challenge for teams, sports and fight promotions.

Forrest Griffin, who sort began the whole Twitter flap with his rape joke/commentary last month on Twitter, says it really shouldn't be that difficult for the fighters to police themselves.

"You should know. You kind of should know. You have a feel for it. For me, it was like a three-hour thing. Three hours before anyone said anything to me, I realized 'I messed up. I shouldn't have said that,'" laughed Griffin. "Someone once said. Twitter is like internet porn, once it's out there, it's out there and there's no getting rid of it."

Griffin joined Stephan Bonnar in the FoxSportsRadio920 studios on Sunday to talk about the current state fighting in the Octagon and outside. Bonnar gave his take on what happened to Griffin, Rashad Evans and then Torres.

"It's one of those things where Forrest said something and everyone got mad. And it's like a little slap on the wrist for Forrest. Then Rashad said something, everyone got mad. Then it was like 'dammit you guys I warned you once.' Then Miguel said something, okay 'we need to make an example somebody.'"

Griffin suggested Torres should've known by then that any sort of sarcastic/joking tweet referencing rape was off limits.

"That was kind of the warning for me, was the warning for everyone. Don't do it. Just stop. It's not perceived well," Griffin told the MMA Fight Corner radio show.

The former light heavyweight champ still likes Twitter because it provides a good forum for discussions.

"I like to say things that are not necessarily inflammatory, but also kind of make you think a lot," said Griffin. "[...] My whole thing is I never meant to hurt people who've been hurt by that. I'm not the kind of person who'd want to hurt people who've been victims of a horrible crime."

Both Griffin and Bonnar appreciate the fact that the UFC has never censored the fighters, but they've definitely gotten the fact that Twitter can be a dangerous place with a fine line to walk.

Source: http://sports.yahoo.com/mma/blog/cagewriter/post/Griffin-says-his-Twitter-warning-was-a-warning-f?urn=mma-wp10769

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Friday, December 16, 2011

AP IMPACT: When your criminal past isn't yours

In this Dec. 18, 2010 photo, Kathleen Casey poses on a street in Cambridge, Mass. A case of mistaken identity landed Casey on the streets without a job or a home. The company hired to run her background check for a potential employer mistakenly found the wrong Kathleen Casey, who lived nearby but was 18 years younger and had a criminal record. (AP Photo/Michael Dwyer)

In this Dec. 18, 2010 photo, Kathleen Casey poses on a street in Cambridge, Mass. A case of mistaken identity landed Casey on the streets without a job or a home. The company hired to run her background check for a potential employer mistakenly found the wrong Kathleen Casey, who lived nearby but was 18 years younger and had a criminal record. (AP Photo/Michael Dwyer)

In this Dec. 18, 2010 photo, Kathleen Casey poses on a street in Cambridge, Mass. A case of mistaken identity landed Casey on the streets without a job or a home. The company hired to run her background check for a potential employer mistakenly found the wrong Kathleen Casey, who lived nearby but was 18 years younger and had a criminal record. (AP Photo/Michael Dwyer)

In this Dec. 18, 2010 photo, Kathleen Casey poses on a street in Cambridge, Mass. A case of mistaken identity landed Casey on the streets without a job or a home. The company hired to run her background check for a potential employer mistakenly found the wrong Kathleen Casey, who lived nearby but was 18 years younger and had a criminal record. (AP Photo/Michael Dwyer)

In this Nov. 10, 2010 photo, Gina Marie Haynes, left, looks over documents with her boyfriend Shawn Hicks before she heads to a job interview in Frisco, Texas. Haynes had just moved from Philadelphia to Texas with her boyfriend in August 2010 and lined up a job managing apartments. A background check found fraud charges, and Haynes lost the offer. (AP Photo/LM Otero)

In this Nov. 10, 2010 photo, Gina Marie Haynes looks over documents before heading to a job interview in Frisco, Texas. Gina Marie Haynes had just moved from Philadelphia to Texas with her boyfriend in August 2010 and lined up a job managing apartments. A background check found fraud charges, and Haynes lost the offer. (AP Photo/LM Otero)

(AP) ? A clerical error landed Kathleen Casey on the streets.

Out of work two years, her unemployment benefits exhausted, in danger of losing her apartment, Casey applied for a job in the pharmacy of a Boston drugstore. She was offered $11 an hour. All she had to do was pass a background check.

It turned up a 14-count criminal indictment. Kathleen Casey had been charged with larceny in a scam against an elderly man and woman that involved forged checks and fake credit cards.

There was one technicality: The company that ran the background check, First Advantage, had the wrong woman. The rap sheet belonged to Kathleen A. Casey, who lived in another town nearby and was 18 years younger.

Kathleen Ann Casey, would-be pharmacy technician, was clean.

"It knocked my legs out from under me," she says.

The business of background checks is booming. Employers spend at least $2 billion a year to look into the pasts of their prospective employees. They want to make sure they're not hiring a thief, or worse.

But it is a system weakened by the conversion to digital files and compromised by the welter of private companies that profit by amassing public records and selling them to employers. These flaws have devastating consequences.

It is a system in which the most sensitive information from people's pasts is bought and sold as a commodity.

A system in which computers scrape the public files of court systems around the country to retrieve personal data. But a system in which what they retrieve isn't checked for errors that would be obvious to human eyes.

A system that can damage reputations and, in a time of precious few job opportunities, rob honest workers of a chance at a new start. And a system that can leave the Kathleen Caseys of the world ? the innocent ones ? living in a car.

Those are the results of an investigation by The Associated Press that included a review of thousands of pages of court filings and interviews with dozens of court officials, data providers, lawyers, victims and regulators.

"It's an entirely new frontier," says Leonard Bennett, a Virginia lawyer who has represented hundreds of plaintiffs alleging they were the victims of inaccurate background checks. "They're making it up as they go along."

Two decades ago, if a county wanted to update someone's criminal record, a clerk had to put a piece of paper in a file. And if you wanted to read about someone's criminal past, you had to walk into a courthouse and thumb through it. Today, half the courts in the United States put criminal records on their public websites.

Digitization was supposed to make criminal records easier to access and easier to update. To protect privacy, laws were passed requiring courts to redact some information, such as birth dates and Social Security numbers, before they put records online. But digitization perpetuates errors.

"There's very little human judgment," says Sharon Dietrich, an attorney with Community Legal Services in Philadelphia, a law firm focused on poorer clients. Dietrich represents victims of inaccurate background checks. "They don't seem to have much incentive to get it right."

Dietrich says her firm fields about twice as many complaints about inaccurate background checks as it did five years ago.

The mix-ups can start with a mistake entered into the logs of a law enforcement agency or a court file. The biggest culprits, though, are companies that compile databases using public information.

In some instances, their automated formulas misinterpret the information provided them. Other times, as Casey discovered, records wind up assigned to the wrong people with a common name.

Another common problem: When a government agency erases a criminal conviction after a designated period of good behavior, many of the commercial databases don't perform the updates required to purge offenses that have been wiped out from public record.

It hasn't helped that dozens of databases are now run by mom-and-pop businesses with limited resources to monitor the accuracy of the records.

The industry of providing background checks has been growing to meet the rising demand for the service. In the 1990s, about half of employers said they checked backgrounds. In the decade since Sept. 11, that figure has grown to more than 90 percent, according to the Society for Human Resource Management.

To take advantage of the growing number of businesses willing to pay for background checks, hundreds of companies have dispatched computer programs to scour the Internet for free court data.

But those data do not always tell the full story.

Gina Marie Haynes had just moved from Philadelphia to Texas with her boyfriend in August 2010 and lined up a job managing apartments. A background check found fraud charges, and Haynes lost the offer.

A year earlier, she had bought a Saab, and the day she drove it off the lot, smoke started pouring from the hood. The dealer charged $291.48 for repairs. When Haynes refused to pay, the dealer filed fraud charges.

Haynes relented and paid after six months. Anyone looking at Haynes' physical file at the courthouse in Montgomery County, Pa., would have seen that the fraud charge had been removed. But it was still listed in the limited information on the court's website.

The website has since been updated, but Haynes, 40, has no idea how many companies downloaded the outdated data. She has spent hours calling background check companies to see whether she is in their databases. Getting the information removed and corrected from so many different databases can be a daunting mission. Even if it's right in one place, it can be wrong in another database unknown to an individual until a prospective employer requests information from it. By then, the damage is done.

"I want my life back," Haynes says.

Haynes has since found work, but she says that is only because her latest employer didn't run a background check.

Hard data on errors in background checks are not public. Most leading background check companies contacted by the AP would not disclose how many of their records need to be corrected each year.

A recent class-action settlement with one major database company, HireRight Solutions Inc., provides a glimpse at the magnitude of the problems.

The settlement, which received tentative approval from a federal judge in Virginia last month, requires HireRight to pay $28.4 million to settle allegations that it didn't properly notify people about background checks and didn't properly respond to complaints about inaccurate files. After covering attorney fees of up to $9.4 million, the fund will be dispersed among nearly 700,000 people for alleged violations that occurred from 2004 to 2010. Individual payments will range from $15 to $20,000.

In an effort to prevent bad information from being spread, some courts are trying to block the computer programs that background check companies deploy to scrape data off court websites. The programs not only can misrepresent the official court record but can also hog network resources, bringing websites to a halt.

Virginia, Arizona and New Mexico have installed security software to block automated programs from getting to their courts' sites. New Mexico's site was once slowed so much by automated data-mining programs that it took minutes for anyone else to complete a basic search. Since New Mexico blocked the data miners, it now takes seconds.

In the digital age, some states have seen an opportunity to cash in by selling their data to companies. Arizona charges $3,000 per year for a bundle of discs containing all its criminal files. The data includes personal identifiers that aren't on the website, including driver's license numbers and partial Social Security numbers.

Other states, exasperated by mounting errors in the data, have stopped offering wholesale subscriptions to their records.

North Carolina, a pioneer in marketing electronic criminal records, made $4 million selling the data last year. But officials discovered that some background check companies were refusing to fix errors pointed out by the state or to update stale information.

State officials say some companies paid $5,105 for the database but refused to pay a mandatory $370 monthly fee for daily updates to the files ? or they would pay the fee but fail to run the update. The updates provided critical fixes, such as correcting misspelled names or deleting expunged cases.

North Carolina, which has been among the most aggressive in ferreting out errors in its customers' files, stopped selling its criminal records in bulk. It has moved to a system of selling records one at a time. By switching to a more methodical approach, North Carolina hopes to eliminate the sloppy record-keeping practices that has emerged as more companies have been allowed to vacuum up massive amounts of data in a single sweep.

Virginia ended its subscription program. To get full court files now, you have to go to the courthouse in person. You can get abstracts online, but they lack Social Security numbers and birth dates, and are basically useless for a serious search.

North Carolina told the AP that taxpayers have been "absorbing the expense and ill will generated by the members of the commercial data industry who continue to provide bad information while falsely attributing it to our courts' records."

North Carolina identified some companies misusing the records, but other culprits have gone undetected because the data was resold multiple times.

Some of the biggest data providers were accused of perpetuating errors. North Carolina revoke the licenses of CoreLogic SafeRent, Thomson West, CourtTrax and five others for repeatedly disseminating bad information or failing to download updates.

Thomson West says it was punished for two instances of failing to delete outdated criminal records in a timely manner. Such instances are "extremely rare" and led to improvements in Thomson West's computer systems, the company said.

CoreLogic says its accuracy standards meet the law, and it seemed to blame North Carolina, saying that the state's actions "directly contributed to the conditions which resulted in the alleged contract violations," but it would not elaborate. CourtTrax did not respond to requests for comment.

Other background check companies say the errors aren't always their fault.

LexisNexis, a major provider of background checks and criminal data, said in a statement that any errors in its records "stem from inaccuracies in original source material ? typically public records such as courthouse documents."

But other problems have arisen with the shift to digital criminal records. Even technical glitches can cause mistakes.

Companies that run background checks sometimes blame weather. Ann Lane says her investigations firm, Carolina Investigative Research, in North Carolina, has endured hurricanes and ice storms that knocked out power to her computers and took them out of sync with court computers.

While computers are offline, critical updates to files can be missed. That can cause one person's records to fall into another person's file, Lane says. She says glitches show up in her database at least once a year.

Lane says she double-checks the physical court filings, a step she says many other companies do not take. She calls her competitors' actions shortsighted.

"A lot of these database companies think it's 'ka-ching ka-ching ka-ching,'" she says.

Data providers defend their accuracy. LexisNexis does more than 12 million background checks a year. It is one of the world's biggest data providers, with more than 22 billion public records on its own computers.

It says fewer than 1 percent of its background checks are disputed. That still amounts to 120,000 people ? more than the population of Topeka, Kan.

But there are problems with those assertions. People rarely know when they are victims of data errors. Employers are required by law to tell job applicants when they've been rejected because of negative information in a background check. But many do not.

Even the vaunted FBI criminal records database has problems. The FBI database has information on sentencings and other case results for only half its arrest records. Many people in the database have been cleared of charges. The Justice Department says the records are incomplete because states are inconsistent in reporting the conclusions of their cases. The FBI restricts access to its records, locking out the commercial database providers that regularly buy information from state and county government agencies.

Data providers are regulated by the Federal Trade Commission and required by federal law to have "reasonable procedures" to keep accurate records. Few cases are filed against them, though, mostly because building a case is difficult.

A series of breaches in the mid-2000s put the spotlight on data providers' accuracy and security. The fallout was supposed to put the industry on a path to reform, and many companies tightened security. But the latest problems show that some accuracy practices are broken.

The industry says it polices itself and believes the approach is working. Mike Cool, a vice president with Acxiom Corp., a data wholesaler, praised an accreditation system developed by an industry group, the National Association of Professional Background Screeners. Fear of litigation keeps the number of errors in check, he says.

"The system works well if everyone stays compliant," Cool says.

But when the system breaks down, it does so spectacularly.

Dennis Teague was disappointed when he was rejected for a job at the Wisconsin state fair. He was horrified to learn why: A background check showed a 13-page rap sheet loaded with gun and drug crimes and lengthy prison lockups. But it wasn't his record. A cousin had apparently given Teague's name as his own during an arrest.

What galled Teague was that the police knew the cousin's true identity. It was even written on the background check. Yet below Teague's name, there was an unmistakable message, in bold letters: "Convicted Felon."

Teague sued Wisconsin's Department of Justice, which furnished the data and prepared the report. He blamed a faulty algorithm that the state uses to match people to crimes in its electronic database of criminal records. The state says it was appropriate to include the cousin's record, because that kind of information is useful to employers the same way it is useful to law enforcement.

Teague argued that the computers should have been programmed to keep the records separate.

"I feel powerless," he says. "I feel like I have the worst luck ever. It's basically like I'm being punished for living right."

One of Teague's lawyers, Jeff Myer of Legal Action of Wisconsin, an advocacy law firm for poorer clients, says the state is protecting the sale of its lucrative databases.

"It's a big moneymaker, and that's what it's all about," Myer says. "The convenience of online information is so seductive that the record-keepers have stopped thinking about its inaccuracy. As valuable as I find public information that's available over the Internet, I don't think people have a full appreciation of the dark side."

In court papers, Wisconsin defended its inclusion of Teague's name in its database because his cousin has used it as an alias.

"We've already refuted Mr. Teague's claims in our court documents," said Dana Brueck, a spokeswoman for Wisconsin's Department of Justice. "We're not going to quibble with him in the press."

A Wisconsin state judge plans to issue his decision in Teague's case by March 11.

The number of people pulling physical court files for background checks is shrinking as more courts put information online. With fewer people to control quality, accuracy suffers.

Some states are pushing ahead with electronic records programs anyway. Arizona says it hasn't had problems with companies failing to implement updates.

Others are more cautious. New Mexico had considered selling its data in bulk but decided against it because officials felt they didn't have an effective way to enforce updates.

Meanwhile, the victims of data inaccuracies try to build careers with flawed reputations.

Kathleen Casey scraped by on temporary work until she settled her lawsuit against First Advantage, the background check company. It corrected her record. But the bad data has come up in background checks conducted by other companies.

She has found work, but she says the experience has left her scarred.

"It's like Jurassic Park. They come at you from all angles, and God knows what's going to jump out of a tree at you or attack you from the front or from the side," she says. "This could rear its ugly head again ? and what am I going to do then?"

___

AP Technology Writer Michael Liedtke in San Francisco contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2011-12-16-US-TEC-Broken-Records/id-329ecd77d35446e3a0e2e916f6f117e8

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Sony eyes Vita push, feels Fitch heat (Reuters)

TOKYO (Reuters) ? Sony Corp, set to report a $1 billion loss this year, is banking on a big slate of new software to drive sales of its new PlayStation Vita handheld games device, even as Fitch downgraded the Japanese electronics giant to a notch above junk.

Welshman Andrew House, who took the top job at Sony Computer Entertainment in September, must plot a much-needed success story for the Vita, negotiating a minefield of consumer gloom and competition from smartphones and tablet PCs such as Apple Inc's iPhone and iPad.

Sony, which has forecast a fourth straight annual loss this year, launches the Vita in Japan this weekend.

It hopes a package of 24 software titles at launch will help the gadget avoid the fate of rival Nintendo's 3DS, which flopped shortly after launch, forcing a hefty price cut.

"It's unprecedented for us to achieve that degree of publisher and development support ... we adopted a different approach to the lead-up to the platform in terms of our relationships with publishers and developers," House told reporters at Sony's Tokyo head office on Thursday.

He said he hoped the Vita would outsell its predecessor, the PlayStation Portable (PSP), which has shipped 73 million units since launching in late-2004.

The videogames unit made a first profit in 5 years in the year to March, as it squeezed production costs for the Playstation 3, boosting profits for the whole company. The unit's sales accounted for more than a tenth of Sony's 7 trillion yen in total revenue.

But costs involved in driving Vita sales may push the unit back into the red this year, adding to Sony's struggle with huge losses in televisions.

Sony needs the Vita to be a hit to ease the pain from its TV business, which is set for an annual loss of $2.2 billion, an eighth straight year of losses. Sony is looking to halve that loss next year, but has given few details on how it plans to get the business back into profit.

FITCH MOVE

The Fitch ratings agency turned up the heat by downgrading Sony to BBB- - a notch above non-investment, or junk, grade - from BBB, citing the group's weakened financial performance and the challenges it faces in recapturing its former strong position in key markets.

"A likely overall FY12 EBIT loss, excluding financial services, and an increase in debt driven by acquisitions will significantly weaken Sony's credit profile," said Nitin Soni, Associate Director in Fitch's Asia-Pacific Telecommunications, Media and Technology team.

Sony said in October it was taking over its mobile phone joint venture with Ericsson for $1.5 billion, and is also leading a group to buy EMI's music publishing operations in a deal valued at $2.2 billion.

"Of course, if the rating is downgraded it makes it more expensive for them to raise money, so it's not good," said Keita Wakabayashi, an analyst at Mito Securities.

"(Sony has) slashed its profit outlook for the current year and even if the North American market has improved slightly, European and Japanese markets and emerging markets are in a severe state. So downgrades are something we'll have to keep in mind."

VITA

The Vita, featuring a 5-inch OLED display and 3G connectivity, sold out in advance bookings in Japan, where buyers have rushed to upgrade from the PSP. Sony has not provided a unit sales target for the Vita.

The United States and Europe may pose a tougher challenge as a February 22 launch date for the Vita comes well after the crucial year-end holiday sales season.

"We've been told the PS Vita sold out on pre-bookings. How it sells next year depends on the software. If they can come up with something like Monster Hunter they will be able to sell a lot, but if they don't, prospects don't look so bright," said Mito's Wakabayashi, referring to a game title that drove sales of the PSP in Japan.

The challenge from smartphones and tablets comes on top of competition from long-standing domestic rival Nintendo, which aims to sell 16 million of its cheaper 3DS handheld games devices by March. Sony on Thursday said it was keeping to its target of selling 15 million PS3 game machines in the year through March.

Another rival, Microsoft, doesn't offer a portable device.

After a slump in sales, Nintendo slashed the price of its handheld gadget in August by about 40 percent to $170, compared with $249 for the PS Vita, or $299 for the 3G version.

The games industry has shrugged off the broader economic gloom and is forecast to top $81 billion by 2016, according to research firm DFC Intelligence, up 23 percent from this year and more than three times the size of the recorded music industry.

Much of that growth is likely to be in online, social and casual games, rather than the traditional hardware model that has been Sony's staple.

Japan's software houses are pouring resources into mobile social gaming, and industry executives have expressed some concern over the future for dedicated handheld gaming devices.

Sony was criticized in June, when it announced the pricing of the Vita, for making the gadget too expensive, and has teamed up with U.S. telecoms firm AT&T as Vita's exclusive carrier. Many U.S. iPhone users have complained that AT&T provided poor connectivity.

Sony shares closed down 1.5 percent on Thursday, their lowest in two weeks.

(Reporting by Isabel Reynolds, Editing by Ian Geoghegan)

Source: http://us.rd.yahoo.com/dailynews/rss/tech/*http%3A//news.yahoo.com/s/nm/20111215/tc_nm/us_sony_vita

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Lindsay Lohan back to court for probation update (AP)

LOS ANGELES ? Lindsay Lohan is due in court Wednesday to give a judge her first progress update under strict new probation requirements intended to keep close tabs on the troubled actress.

Lohan has been reporting regularly for work at the Los Angeles County morgue since being repeatedly threatened with a long jail sentence if she failed to complete the terms of her probation, which include community service and counseling sessions.

The hearing is without the usual drama that precedes Lohan's recent court appearances, which have focused on the actress' shortcomings by missing court-ordered therapy sessions and getting booted from a community service assignment at a women's shelter. The "Mean Girls" star spent less than five hours at a jail last month as part of a 30-day sentence imposed by Judge Stephanie Sautner for Lohan's continued misbehavior.

The judge is requiring the starlet to report on her progress monthly and it appears Lohan has been successful in meeting the goals of Wednesday's hearing.

"She's been doing fine," Deputy Chief Coroner Ed Winter said Tuesday, saying the actress has been showing up, working and leaving without incident.

He said he did not know how many hours Lohan had completed.

Her spokesman, Steve Honig, said Lohan has met or exceeded the terms of her probation imposed by Sautner last month.

"She's working very diligently to keep up her days so she can finish up with probation," he said.

Lohan remains on probation for a 2007 drunken driving case and a misdemeanor grand theft case filed after she took a $2,500 necklace without permission.

She has consistently struggled with the terms of her various sentences, which have included jail terms, rehab, community service and counseling.

Her appearance Wednesday comes days before a Playboy issue featuring Lohan in a mostly-nude pictorial hits newsstands. The magazine was forced to release the issue online early after photos of the Marilyn Monroe-inspired spread leaked out online.

___

Follow Anthony McCartney at http://twitter.com/mccartneyAP

Source: http://us.rd.yahoo.com/dailynews/rss/celebrity/*http%3A//news.yahoo.com/s/ap/20111214/ap_en_ce/us_people_lindsay_lohan

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Wednesday, December 7, 2011

Microsoft delays Windows Phone launch in China until next year

Next week will mark the one-year anniversary of Microsoft's declaration that Windows Phone 7 would come to China during the second half of 2011, but the company has officially stated that it's not going to make the December 31st deadline. Instead, phones with the OS are now expected to hit the nation sometime in the first half of 2012. Microsoft mentioned that the delay is at least in part due to trying to ensure that Chinese citizens will have a good experience using the platform (Nokia mentioned that localization is needed in certain aspects of its phones to keep in line with the government's media censorship policy); it wouldn't come as much of a surprise if we see the first batch of phones -- likely to be made by Nokia, Huawei and / or ZTE, at least -- come with a fresh install of Windows Phone Tango on them, but that's mere speculation for now.

Microsoft delays Windows Phone launch in China until next year originally appeared on Engadget on Mon, 05 Dec 2011 16:44:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2011/12/05/microsoft-delays-windows-phone-launch-in-china-until-next-year/

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NeuroLogica Blog ? Organic Food, Pesticides, and Cancer

I recently received the following question:

My wife is worried about eating vegetables that have been treated with pesticides for fear that it increases risk of cancer. I have looked at some of the books she has read that pushes organic eating and I was not impressed with the authors credentials or citations. Is there any scientific evidence that supports the assertion that eating organic vegetables will reduce the risk of cancer?

Organic farming is a complex issue, and one of those issues shrouded with ideological belief to the point that it is often difficult to find objective evidence and opinion. There are also many issues within the organic farming framework. Is organic farming cost effective, more sustainable, capable of feeding the world, better for the environment, and better for human health? There is also the more fundamental question ? what, exactly, constitutes organic farming? I find that often it is a catch-all phrase for any farming practice deemed to be more sustainable or environmentally friendly, or any practice considered ?natural?. Unfortunately ?natural? is a vague term.

Here is part of the USDA definition for organic:

?Organic agriculture is an ecological production management system that promotes and enhances biodiversity, biological cycles and soil biological activity. It is based on minimal use of off-farm inputs and on management practices that restore, maintain and enhance ecological harmony.

The devil, as always, is in the details ? what, operationally, does this mean? Here there is agreement on some details but not on others. You can search the USDA site linked to above for more details.

My opinion is that farming practices should each be judged on their own merits, utilizing the best evidence available. I find this situation similar to the ?alternative medicine? category, which is sweeping in its philosophy but with no clear operational definition, and eager to claim for itself practices which are solidly science-based (like legitimate uses of nutrition, physical therapy, or even exercise). Organic farming seems better than CAM as a category, but still represents a false dichotomy, in my opinion. Is any sustainable practice organic? What difference does it make what the source of a pesticide is?

I agree with many of the organic principles ? like sustainability, low environmental impact, and food safety. Who would be against sustainability in agriculture? I would prefer, however, an evidence- based rather than philosophy-based (which, for organic farming, is essentially the naturalistic fallacy) approach to what works.

My big problem with the ?organic? label is when it is applied to produce rather than farming practice. It is used as a marketing device, implying greater nutrition and safety. However, the evidence is simply not there to back up such claims.

A recent review of the published research from 1958-2008 showed that the evidence does not support the conclusion that there is any nutrition-related health benefit to eating organic food. Fifty years is a long time for organic food advocates to have made this case, but they haven?t. It also seems, however, that there hasn?t been a great deal of high quality research in this area, so it seems that the confidence in this conclusion of a lack of benefit is still open to better research.

Other studies look simply at the nutritional content of organic vs traditionally farmed produce. ?The same researchers did a?systematic review of this question and found:

On the basis of a systematic review of studies of satisfactory quality, there is no evidence of a difference in nutrient quality between organically and conventionally produced foodstuffs. The small differences in nutrient content detected are biologically plausible and mostly relate to differences in production methods.

Some studies have found small increases in nutritional content in organic produce. However, it is possible that this is mostly or even entirely due to the fact that organic produce tends to be a little smaller with lower water content, and so higher concentrations of measured nutrients. It is still not clear, therefore, that eating organic produce will deliver more overall nutrients than eating traditional produce, and if there is a difference if it is clinically relevant to health.

This brings up yet another issue ? organic produce is more expensive. The USDA lists comparisons of organic and conventional produce prices and finds that there is a premium for organic produce. Looking through some of the tables is seems that organic produce is more than twice as expensive as conventional produce. Another USDA site, however, finds that 40% of organic farmers at farmers markets did not charge a premium for their organic produce, although this varied by season and crop.

Regardless of the reasons for the price difference, there is still a premium for most organic crops. Given the small, if any, nutritional advantage, it?s possible that higher organic food prices might result in a net decrease in consumption of fruits and vegetables. ?In any case, the evidence for nutritional health benefits does not support paying a higher premium for organic produce (although there are many other reasons why someone might prefer organic and be willing to pay a higher price, but they are separate issues outside the scope of this post).

What about the issue of pesticides? Here is where the ?organic? concept is most guilty of committing the naturalistic fallacy. The organic label does not mean pesticide free. It just means that ?naturally derived? pesticides are used instead of ?artificial? pesticides. There is no a priori reason, however, to assume that naturally-derived pesticides are safer. It mostly means that they are less well-researched, because of the false assumption that they are safer.

Again ? this is a very complex area in itself. To summarize what I have found: pesticides are poisons, there is no question, and all efforts should be made to limit human and environmental exposure. This does not mean they cannot be used safely, but precautions need to be taken. There is no reason to assume organic pesticides are safe or safer than conventional pesticides. There is evidence that organic pesticides are often less effective, requiring greater amounts to be used, which can have a net negative effect on the environment. When studied it turns out that organic pesticides can also have carcinogenic effects.

Here is a good summary of the evidence.

While organic produce has lower levels of pesticides than conventional produce, there is no evidence that these low levels of pesticides pose any health risk. For those who wish to minimize their pesticide exposure, just in case, buying organic may not even be the best option. Washing your fruits and vegetables works quite well?in reducing pesticide residue. It?s also cheaper than buying organic.

Conclusion

While the overall issue of organic farming is complex with many sub-issues, the question of health benefits is perhaps the easiest to answer at this time. After decades of research there is no evidence for any health benefits to eating organic vs conventional food. Nutritional value is either slightly higher or not significantly different in organic produce, but even with a generous interpretation is not clinically significant.

The issue of pesticides has not been completely resolved, but at present the levels of pesticides in conventional produce is likely to be below safety limits, and there is no real reason to conclude that ?organic? pesticides are any safer. Further, the most effective means of minimizing pesticide exposure is simply to thoroughly wash your fresh produce.

Source: http://theness.com/neurologicablog/index.php/organic-food-pesticides-and-cancer/

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Tuesday, December 6, 2011

Peter Jackson's company wraps doc on West Memphis 3 (Reuters)

LOS ANGELES (TheWrap.com) ? Peter Jackson's production company, WingNut Films, announced on Sunday that it has completed a documentary about the West Memphis Three -- the three men whose murder convictions in Arkansas were overturned this past August.

Amy Berg directed "West of Memphis," and one of the documentary's three main subjects, Damien Echols, produced the movie, along with his wife, Lorri Davis.

Jackson and his production partner, Fran Walsh, helped fund the men's legal defense.

Jackson and Walsh became involved in 2005, when they helped to reinvigorate the then-stagnant case by funding a new investigation.

Echols, Jason Baldwin and Jessie Misskelley Jr. were teenagers when they were arrested for the murders of Christopher Byers, Steven Branch and Michael Moore in the small town of West Memphis, Arkansas, in 1993.

Echols, Baldwin and Misskelley served 18 years and 17 days in prison for the murders.

But controversy surrounded the convictions. Supporters of the convicted men said that prosecutors failed to articulate a strong motive for the crimes. Earlier this year, efforts to overturn the convictions intensified after new evidence showed no traces of DNA from the men at the crime scene. Evidence also showed that another person may have been there.

Over the years, the three received support from celebrities including Johnny Depp, Eddie Vedder and Henry Rollins.

"Seven years ago, Fran and I began this journey with Damien and Lorri, having no idea where it would lead," Jackson said in a written statement. "We now realize that journey is not over, that even though these men have been released from prison, they are not free. Our hope is that continuing evidence testing and further investigation will lead to the unmasking of the killer of these children and that one day Damien, Jason and Jessie will be exonerated."

The story of Echols, Baldwin and Misskelley already has been the subject of several documentaries. Filmmakers Joe Berlinger and Bruce Sinofsky made the 1996 documentary "Paradise Lost" and a 2000 sequel, "Paradise Lost 2: Revelations."

Their third film, "Paradise Lost: Purgatory" is scheduled to be released in January.

Canadian director Atom Egoyan plans to start shooting a movie based on the men in early spring 2012.

Source: http://us.rd.yahoo.com/dailynews/rss/movies/*http%3A//news.yahoo.com/s/nm/20111205/film_nm/us_memphis

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Monday, December 5, 2011

100,000 Wreaths Headed To Arlington National Cemetery

PORTLAND, Maine -- Twenty years ago, wreath company owner Morrill Worcester and a dozen other people laid 5,000 wreaths on headstones at Arlington National Cemetery. It was Worcester's way of giving thanks to the nation's veterans with leftover unsold wreaths.

This year, Worcester has arranged for up to 100,000 wreaths to be placed on gravesites at the military cemetery Dec. 10 in his biggest wreath-laying undertaking yet.

A convoy of more than 20 trucks left Worcester Wreath Co. in the eastern Maine town of Harrington on Sunday to begin the six-day journey to the cemetery in Arlington, Va., outside Washington, the final resting place for hundreds of thousands of veterans and a tourist site that draws 4 million visitors a year. Along the way, there'll be ceremonies at schools, veterans' homes and in communities in Maine, Massachusetts, New York, New Jersey, Pennsylvania, Delaware and Maryland.

Worcester never expected the wreath-laying effort to grow from a single tractor-trailer carrying a few thousand wreaths to 84 big rigs delivering wreaths to Arlington and hundreds of locations. Besides the Arlington ceremony, his Wreaths Across America organization has also organized more than 700 other ceremonies at veterans' cemeteries and monuments across the country and overseas involving 225,000 wreaths.

"We haven't really tried to push it; it's really just grown on its own," Worcester said. "We have a hard time keeping up with it."

Worcester, who has never served in the military, came up with the idea of a wreath-laying ceremony 20 years ago when he found himself with an extra 5,000 wreaths in December, too late to bring to market. He decided upon Arlington National Cemetery, which he had visited as a child.

After that first year, Worcester continued donating wreaths and holding ceremonies at the cemetery. The event remained relatively small with little fanfare until a photo, showing thousands of green wreaths with red ribbons nestled against headstone on a snow-covered ground, made its way around the Internet about five years ago.

After that, Worcester got thousands of emails and letters from people wanting to donate, and inquiries from others asking how they could hold wreath-laying ceremonies of their own to pay tribute to those who have served in the military. So he and his wife founded the nonprofit Wreaths Across America to take in donations and organize hundreds of wreath-laying ceremonies at veterans' cemeteries.

Wreaths Across America put 24,000 wreaths on Arlington headstones last year, and initially hoped to put them on virtually all 220,000 headstones this year. That initiative fell short, but Worcester said he's still pleased that they'll be able to put out 100,000 of the laurels.

Of the 325,000 wreaths in all of this year's ceremonies, Worcester is donating 25,000. His company makes the rest, but they are paid for through donations from groups and individuals and through corporate sponsorships.

The growth of the event doesn't surprise Joanne Patton of Hamilton, Mass., the daughter-in-law of World War II Gen. George S. Patton and the widow of Patton's son, Maj. Gen. George S. Patton IV, who is buried in Arlington.

On Monday, Patton will receive one of Worcester's wreaths in a ceremony in Topsfield, Mass., which she will then lay on a tank in Patton Park in Hamilton, Mass. She has participated in past Wreaths Across America events as well.

"It's an amazing expression of honoring the spirit of service," she said.

Figuring out the logistics of resting so many wreaths at Arlington National Cemetery was complex enough when there were only 5,000 to worry about, said Wayne Hanson, who is in charge of coordinating the ceremony at Arlington. If the weather is nice, Hanson expects more than 10,000 people to participate in Saturday's event.

Hanson is optimistic that some year soon all the Arlington headstones will have wreaths placed on them for the ceremony.

"We can work toward doing the whole cemetery for our 25th anniversary," he said.

___

RELATED VIDEO: Obama Lays Wreath At Arlington National Cemetery '; var coords = [-5, -72]; // display fb-bubble FloatingPrompt.embed(this, html, undefined, 'top', {fp_intersects:1, timeout_remove:2000,ignore_arrow: true, width:236, add_xy:coords, class_name: 'clear-overlay'}); });

Source: http://www.huffingtonpost.com/2011/12/04/arlington-national-cemetery-wreaths_n_1128190.html

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Sunday, December 4, 2011

Cancer cells' DNA repair disrupted to increase radiation sensitivity

Thursday, December 1, 2011

Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells' sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research.

Researchers would to like see their laboratory findings ? published in the journal's Dec. 5 print edition ? lead to safer, more effective combination therapies for hard-to-treat pediatric brain cancers like medulloblastoma and high-grade gliomas. To this end, they are starting laboratory tests on brain cancer cells.

"Children with pediatric brain cancers don't have very many options because progress to find new treatments has been limited the last 30 years," said Rachid Drissi, PhD, principal investigator on the study and a researcher in the Division of Oncology at Cincinnati Children's. "The ability to make cancer cells more sensitive to radiation could allow physicians to use lower radiation doses to lessen side effects. Too many children with brain cancer can develop disabilities or die from treatment."

Before treating cells with ionizing radiation, the researchers blocked an enzyme called telomerase, found in over 90 percent of cancer cells but barely detectable in most normal human cells. In cancer cells, telomerase helps maintain the length of caps on the ends of chromosomes called telomeres. This helps cancer cells replicate indefinitely, grow and spread, Drissi said.

Unraveling DNA repair

Found on chromosomes in both cancerous and normal cells, telomeres are analogous to plastic caps that keep shoestring ends from unraveling. Telomeres help preserve DNA stability in cells by containing genetic miscues. This helps explain why cells with maintained or long telomeres appear to be more resistant to radiation.

In normal cells lacking the telomerase enzyme, telomeres get shorter each time cells divide. They continue doing so until normal cells stop dividing, reaching a condition called senescence. If this first cell-cycle "stop sign" is bypassed, cells continue dividing until telomeres become critically short and reach a second stopping point, when most cells die. In rare instances, cells bypass this second "stop sign" and survive. This survival is often associated with telomerase activation and the onset of cancer.

This was the basis for experiments Drissi and his colleagues conducted to compare the radiation sensitivity and survivability of cells based on telomere length. They also monitored DNA repair responses in the cells by looking for specific biochemical signs that indicate whether the repair systems are working.

The tests involved normal human foreskin cells ? called fibroblasts ? and human cervical carcinoma cells. They exposed the cells to ionizing radiation and analyzed DNA repair responses as telomeres became progressively shorter. In the cervical cancer cells, researchers blocked the telomerase enzyme before radiation treatment to induce progressively shorter telomeres.

Both late-stage noncancerous cells with shorter telomeres, and cancer cells with induced shorter telomeres, were more radiosensitive and died more quickly, according to the study.

Among cancer cells with maintained telomere length, close to 10 percent receiving the maximum dose of ionizing radiation used in the study (8 Gy, or Gray Units) survived the treatment. None of the cancer cells with the shortest telomeres survived that exposure.

Researchers said the cancer cells became more radiosensitive because material inside the chromosomes ? called chromatin ? compacted as telomeres became shorter. Compacted chromatin then disrupted the biochemical signaling of a protein called ATM (ataxiatelangeietasia mutated).

ATM is a master regulator of DNA repair and cell division. It sends signals to activate other biochemical targets (H2AX, SMC1, NBS1 and p53) that help direct DNA repair and preserve genetic stability. In telomere-shortened cancer cells, the compacted chromatin inhibited ATM signaling to all of the chromatin-bound targets tested in the study. This disrupted DNA repair responses and increased radiation sensitivity.

Testing brain cancer cells

The researchers are now testing their findings in cells from hard-to-treat pediatric brain tumors. These tests begin as Drissi's laboratory also leads correlative cancer biology studies of tumor samples from a current clinical trial. The trial is evaluating telomere shortening as a stand-alone therapy for pediatric cancers.

Managed through the National Institutes of Health's Children's Oncology Group (COG), the multi-institutional Phase 1 trial is testing the safety and tumor response capabilities of the drug Imetelstat, which blocks telomerase in cancer cells. Drissi serves on the clinical trial committee along with Maryam Fouladi, MD, MSc, and medical director of Neuro-Oncology at Cincinnati Children's. She leads the medical center's clinical participation in the trial.

Drissi and Fouladi are starting preparatory work to develop, and seek approvals for, a possible clinical trial to test telomere shortening and radiation treatment as a safer, more effective treatment for pediatric brain tumors.

###

Cincinnati Children's Hospital Medical Center: http://www.cincinnatichildrens.org

Thanks to Cincinnati Children's Hospital Medical Center for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/115646/Cancer_cells__DNA_repair_disrupted_to_increase_radiation_sensitivity

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Saturday, December 3, 2011

PFT: Eagles continue search for rock bottom

Steve Maneri,  Troy PolamaluAP

Congratulations, Steelers.? Your use of a term other than ?concussion? has officially given the condition the same stigma as herpes, HIV, and leprosy.

Why else would safety Troy Polamalu refuse to say on Friday whether he suffered a concussion five nights earlier against the Chiefs?? Andrew Stockey of WTAE asked the question, and Polamalu took the fifth on whether he has sustained his eighth known concussion.

Regardless of the reason, it?s bizarre that a team and a player would be so defiant when it comes to acknowledging what anyone who has had fewer than 50 concussions realizes:? Against the Chiefs, Troy Polamalu sustained a concussion.

The mere fact that he refused to answer the question confirms it.

Perhaps the Steelers have avoided the ?C? word in order to keep a truly independent neurologist out of the team?s and the player?s business.? Or maybe the goal is to subtly influence players to try to conceal their ?concussion-like symptoms? whenever and wherever possible, as part of facing down the demons inherent to the sport.

?That?s the fear, I think, that any player faces, and that?s the fear that anybody, any individual faces ? overcoming any certain fears of being a coward, you know, or letting your teammates down or turning down a hit,? Polamalu said regarding whether he?s concerned about a hit to the head that could cause long-term damage.? ?That?s the beautiful thing about sports, is these fears are right in your face and it?s pretty obvious if you turn them down or not.? I have the fear.? No question about it.? But I?m willing to fight it, for sure.?

I continue to believe that football players who are lucid and capable of making informed decisions should be permitted to assume all risks associated with playing football, even if they are still suffering from concussion-like (or concussion-actual) symptoms.? For now, the issue is whether the Steelers will fully embrace and respect the league?s current rules, which contemplate a full tearing down of the wall that resides between ?rubbing dirt on it? and acknowledging that serious, long-term damage could be done to a fairly vital organ.

Those rules entail encouraging players to be candid, not secretive, about the condition of their brains.? Polamalu?s simple refusal to admit the obvious shows conclusively that, within the Steelers organization, there?s an implicit understanding that confronting the fear of serious injury includes shrugging off the blows to the head that don?t create serious problems in the short term.

Source: http://profootballtalk.nbcsports.com/2011/12/01/the-eagles-continue-to-search-for-rock-bottom/related

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YouTube goes under the knife, new homepage and social integration emerge (video)

Falling into lockstep with Google's quest to redesign everything, YouTube officially unveiled a radical new look for its twenty billion strong video site. Now sporting a more somber look, the homepage is now dominated by a center feed hosting content, which is flanked on its left by a list of channels in a quasi-navigation bar. Besides hosting channels, that navbar also features Google+ and (opt-in) Facebook tabs, allowing you to peruse content friends are sharing and interacting with. Also tweaked are channels, which are now more easily customizable thanks to the addition of snazzy new templates. To our eyes the whole shebang looks like a well-oiled augmented Cosmic Panda coupled with some slick social integration, but don't take our word for it, a video explaining the changes awaits you after the break.

Continue reading YouTube goes under the knife, new homepage and social integration emerge (video)

YouTube goes under the knife, new homepage and social integration emerge (video) originally appeared on Engadget on Thu, 01 Dec 2011 17:50:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2011/12/01/youtube-goes-under-the-knife-new-homepage-and-social-integratio/

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Friday, December 2, 2011

Zynga IPO values company as high as $9.04 billion (Reuters)

(Reuters)- Zynga Inc plans to sell an 11.1 percent stake in a scaled-back initial public offering that would value the Facebook game maker at as much as $9 billion on a fully diluted basis.

The leading social games maker plans to sell 100 million new shares at between $8.50 and $10 each, according to a U.S. regulatory filing on Friday.

At the midpoint price, the IPO could raise $925 million, which would make it the largest from a U.S. Internet company since Google Inc raised $1.7 billion in 2004.

Five-year-old Zynga made its name on viral games such as "FarmVille," among the most popular on the Facebook social network. While Zynga's games are free to play, the company makes money from selling virtual items -- such as tractors and weapons -- that players then use.

Based on a fully diluted share count of 904 million, which includes existing shares and stock options, the IPO price values Zynga at $7.7 billion to $9.04 billion.

In a filing two weeks ago, the company said a third-party analysis had valued it at $14.05 billion. While the valuation has been cut, Zynga would still be among the largest publicly traded U.S. game developers after it debuts on Nasdaq under the "ZNGA" symbol.

Video game developer Activision Blizzard Inc currently has the industry's highest market value of $14.2 billion, followed by Electronic Arts Inc at $7.7 billion.

Zynga's debut will follow IPOs this year from Groupon Inc and LinkedIn Corp, which helped revive a market that had sputtered in recent years. Facebook is gearing up to go public next year.

Mark Pincus, a serial entrepreneur before he founded Zynga, will hold a class of shares with 70 times more voting power than the regular stock that will be sold in the offering.

Google, one of the early investors in Zynga, will be offering about 1.7 million shares, according to a regulatory filing. Other companies selling shares include Institutional Venture Partners and Union Square Ventures

Deep-pocketed rivals from Walt Disney Co to Electronic Arts are starting to muscle in on Zynga's turf.

The company said its IPO represented 14.3 percent of 699 million common shares, excluding restricted stock.

(Reporting by Liana B. Baker in New York and Brenton Cordeiro in Bangalore; Editing by Lisa Von Ahn)

Source: http://us.rd.yahoo.com/dailynews/rss/internet/*http%3A//news.yahoo.com/s/nm/20111202/tc_nm/us_zynga_ipo

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Monday, November 28, 2011

Pakistan says NATO ignored its pleas during attack

Supporters Pakistani religious party Jamatud Dawa burn representation of the U. S. flag and posters of US President Obama and NATO's general during a protest rally to condemn NATO strikes on Pakistani posts, in Multan, Pakistan, on Monday, Nov 28, 2011. The NATO airstrikes that killed 24 Pakistani soldiers went on for almost two hours and continued even after Pakistani commanders had pleaded with coalition forces to stop, the army claimed Monday in charges that could further inflame anger in Pakistan. (AP Photo/Khalid Tanveer)

Supporters Pakistani religious party Jamatud Dawa burn representation of the U. S. flag and posters of US President Obama and NATO's general during a protest rally to condemn NATO strikes on Pakistani posts, in Multan, Pakistan, on Monday, Nov 28, 2011. The NATO airstrikes that killed 24 Pakistani soldiers went on for almost two hours and continued even after Pakistani commanders had pleaded with coalition forces to stop, the army claimed Monday in charges that could further inflame anger in Pakistan. (AP Photo/Khalid Tanveer)

Pakistani lawyers rally to condemn NATO strikes on Pakistani troops, in Karachi, Pakistan, on Monday, Nov 28, 2011. The NATO airstrikes that killed 24 Pakistani soldiers went on for almost two hours and continued even after Pakistani commanders had pleaded with coalition forces to stop, the army claimed Monday in charges that could further inflame anger in Pakistan. Placard on right reads " Go ahead Pakistan army we are with you."(AP Photo/Shakil Adil)

A Pakistani driver covers a NATO vehicle parked at Pakistani border Chaman which was closed for NATO supply trucks on Monday, Nov 28, 2011. The border closure is in response to NATO airstrikes that killed 24 Pakistani soldiers went on for almost two hours and continued even after Pakistani commanders had pleaded with coalition forces to stop, the army claimed Monday in charges that could further inflame anger in Pakistan. (AP Photo/Shah Khalid)

A Pakistani loader walks past NATO trucks parked at Pakistani border Chaman which was closed for NATO supply trucks on Monday, Nov 28, 2011. The border closure is in response to NATO airstrikes that killed 24 Pakistani soldiers went on for almost two hours and continued even after Pakistani commanders had pleaded with coalition forces to stop, the army claimed Monday in charges that could further inflame anger in Pakistan. (AP Photo/Shah Khalid)

Pakistani lawyers rally to condemn NATO strikes on Pakistani troops, in Karachi, Pakistan, on Monday, Nov 28, 2011. The NATO airstrikes that killed 24 Pakistani soldiers went on for almost two hours and continued even after Pakistani commanders had pleaded with coalition forces to stop, the army claimed Monday in charges that could further inflame anger in Pakistan. (AP Photo/Shakil Adil)

(AP) ? The NATO airstrikes that killed 24 Pakistani soldiers lasted almost two hours and continued even after Pakistani commanders had pleaded with coalition forces to stop, the army claimed Monday in charges that could further inflame anger in Pakistan.

NATO has described the incident as "tragic and unintended" and has promised a full investigation.

Unnamed Afghan officials have said that Afghan commandos and U.S. special forces were conducting a mission on the Afghan side of the border and received incoming fire from the direction of the Pakistani posts. They responded with airstrikes.

Ties between Pakistan and the United States were already deteriorating before the deadly attack and have sunk to new lows since, delivering a major setback to American hopes of enlisting Islamabad's help in negotiating an end to the 10-year-old Afghan war.

Army spokesman Maj. Gen. Athar Abbas said the Pakistani troops at two border posts were the victims of an unprovoked aggression. He said the attack lasted almost two hours and that commanders had contacted NATO counterparts while it was going on, asking "they get this fire to cease, but somehow it continued."

The Pakistan army has previously said its soldiers retaliated "with all weapons available" to the attack.

The poorly defined, mountainous border has been a constant source of tension between Pakistan and the United States. NATO officials have complained that insurgents fire from across the frontier, often from positions close to Pakistani soldiers who have been accused of tolerating or supporting the militants. NATO and Afghan forces are not allowed to cross over into Pakistan in pursuit of militants.

Saturday's strikes have added to popular anger in Pakistan against the U.S.-led coalition presence in Afghanistan. Many in the army, parliament, general population and media already believed that the U.S. and NATO are hostile to Pakistan and that the Afghan Taliban are not the enemy.

By claiming it was the victim of unprovoked aggression, the Pakistan army is strengthening this narrative.

While the United States is widely disliked in Pakistan, the army has accepted billions in American aid over the last 10 years in return for its cooperation in fighting al-Qaida. It has been accused of fomenting anti-American sentiment in the country to extract better terms in what is essentially a transactional and deeply troubled relationship with Washington.

Saturday's deadly incident also serves to shift attention away from the dominant perception of the Pakistani army in the West over the last five years ? that of an unreliable ally that supports militancy. That image was cemented after al-Qaida's chief Osama bin Laden was found to have been hiding in an army town close to the Pakistani capital when he was killed.

For Pakistan's weak and much criticized elected government, Saturday's airstrikes provide a rare opportunity to unite the country and a momentary relief from attack by rivals eyeing elections in 2013 or sooner.

By contrast, deaths of soldiers and civilians in attacks by militants, some with alleged links to the country's spy agencies, are often greeted with official silence.

Abbas dismissed Afghanistan's claims that the joint Afghan-NATO troops were fired upon first.

"At this point, NATO and Afghanistan are trying to wriggle out of the situation by offering excuses," he said. "Where are their casualties?"

Abbas said the two military posts, named "Volcano" and "Golden," were located on a ridge in Mohmand region around 300 yards (meters) from the border with Afghanistan. He said their exact location had been provided to NATO and that the area had recently been cleared of militants.

Hours after the attack on Saturday, Pakistan closed its western border to trucks delivering supplies to NATO troops in Afghanistan, demanded that the U.S. abandon an air base inside Pakistan used to operate drone strikes, and said it will review its cooperation with the U.S. and NATO.

However, a complete breakdown in the relationship between the United States and Pakistan is considered unlikely. Pakistan relies on billions of dollars in American aid, and the U.S. needs Pakistan to push Afghan insurgents to participate in peace talks.

After the bin Laden raid, ties almost collapsed but slowly resumed, albeit at a lower level and with lower expectations on the American side.

A year ago, a U.S. helicopter attack killed two Pakistani soldiers posted on the Afghan-Pakistani border, prompting the army to close one of the border crossings. A joint investigation by the two nations found that Pakistani troops had fired first at the U.S. helicopters. The investigation found that the shots were probably meant as warnings after the choppers passed into Pakistani airspace. The U.S. apologized, and the border was reopened.

______

Associated Press writer Deb Reichmann contributed to this report from Kabul, Afghanistan.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2011-11-28-AS-Pakistan/id-91ce228d6efe450eaec72d3ea4b34de1

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US officials vow full probe into Pakistan border incident (Star Tribune)

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Sunday, November 27, 2011

Mice with fewer insulin-signaling receptors don't live longer

Thursday, November 24, 2011

Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even if their bodies were less responsive to insulin, the hormone that lowers blood sugar.

A new study from The University of Texas Health Science Center San Antonio challenges this. Knocking out one copy of the gene failed to increase the life span of male mice, and it only modestly increased the life span of female littermates.

Martin Adamo, Ph.D., professor of biochemistry, and Arlan Richardson, Ph.D., professor of cellular and structural biology, lead the laboratories that conducted the study. "Our data show insufficiency of this insulin-signaling gene does not produce a robust increase in life span as previously reported in invertebrates," Dr. Richardson said.

Dr. Adamo said: "This demonstrates that reducing insulin signaling through the IGF1 pathway in mammals does not play the same role in aging that is observed in invertebrates."

A receptor is a molecule on a cell's membrane that receives chemical signals. Knocking down the genetic instructions that make IGF1 receptors results in reduced insulin signaling.

###

The study is described Nov. 23 in the journalPLoS ONE.

University of Texas Health Science Center at San Antonio: http://www.uthscsa.edu/hscnews

Thanks to University of Texas Health Science Center at San Antonio for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 77 time(s).

Source: http://www.labspaces.net/115462/Mice_with_fewer_insulin_signaling_receptors_don_t_live_longer

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Saturday, November 26, 2011

Oil near $97 amid light Thanksgiving volume

(AP) ? Oil prices rose slightly to near $97 a barrel Thursday in Asia amid light trading volume ahead of a U.S. holiday.

Benchmark crude for January delivery was up 43 cents at $96.60 a barrel at late afternoon Singapore time in electronic trading on the New York Mercantile Exchange. The contract fell $1.84 to settle at $96.17 in New York on Wednesday.

Brent crude for January delivery rose 50 cents to $107.52 a barrel on the ICE Futures Exchange in London.

Markets in the U.S. are closed Thursday for the Thanksgiving holiday.

Crude has fallen from above $103 last week amid investor concern that Europe's debt crisis will undermine global economic growth and oil demand.

However, crude inventories have dropped in recent months in the U.S. and Europe. Crude supplies fell by 6.2 million barrels last week and are about 8 percent below year-earlier levels, the Energy Department's Energy Information Administration said Wednesday.

"The low inventory situation has prevented oil prices from falling sharply," Bank of America Merrill Lynch said in a report. "But eventually, deteriorating financial conditions could start to impact economic activity and bring oil prices somewhat lower."

Bank of America said it expects Brent crude to average $104 in the first quarter of next year.

Some analysts predict robust growth in demand for commodities from developing countries will outstrip production capacity increases and push prices higher.

"We believe that the oil market has been too focused on the downside risks to prices and not focused enough on the upside risk should the economy avoid recession," Goldman Sachs said in a report.

In other Nymex trading, heating oil rose 1 cent to $2.98 per gallon and gasoline futures gained 2.4 cents to $2.54 per gallon. Natural gas was steady at $3.61 per 1,000 cubic feet.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2011-11-24-Oil-Prices/id-88540cd5bbbd4a3ebfe15ba94fed5457

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